Monday, October 29, 2007

cancer

Definition: Mutation of DNA in a single cell to divide without control. If
unchecked Cancer cells can invade nearby tissues and spread through the bloodstream and lymphatic system to other parts of the body (metastasis) .
Cancer cells are smart in avoiding natural cell death and settle in most conducive locations like bones & other organs where nourishment supply is abundant.
A tumor is an abnormal mass of tissue developed from excessive cell division (mitotic activity)which has no useful body function. It may be either benign or malignant.
Real battle is on in the metastasis stage between the Immune system and the Tumor.

Immune System- As I understood

Human Immune System:1.Cellular immunity rooted in cells.
2.Humoral immunity by chemical factors circulating in blood & tissues.
Antigens (short for antibody generators) and are defined as substances that bind to specific immune receptors and elicit an immune response.
Granulocytes-belong to Phagocytes which act on the invadors at the site to stop infection.

Macrophages releases Cytokines. A Cytokine is tumor necrosis factor which destroys cancer cells & tumors.

Lymphocytes
A lymphocyte is a type of white blood cell (leukocytes) in the vertebrate immune system.
Lymphocytes are responsible for immune responses. There are two main types of lymphocytes: B cells and T cells.
* B lymphocytes (often simply called B cells) produced by bone marrow and mature there.
* T lymphocytes (likewise called T cells).precursors of T cells leave the bone marrow and mature in the thymus
Large granular lymphocytes are more commonly known as the natural killer cells (NK cells). The small lymphocytes are the T cells and B cells
Most of the T cells in the body belong to one of two subsets. CD4 & CD8 immune cells which activate other immune factors to work against the disease.
Plant & animal aminoacids-complement which triggers chemical factors to encounter the foreign invaders.
CD8+ T cells are cytotoxic T lymphocytes (CTLs)which secrete molecules that destroy the cell to which they have bound.

Effects of few Cytokines & Interleukins (1-18):

IL-1 Causes maturity of immune cells to fight pathogens & cancer.
IL-1 & Interferon causes sleep when we lie.
IL-1,Interferon+tumor necrosis factor- combine to control zinc metabolism& withhold minerals in tissues to strengthen immune response against infections,tumors & virus.
IL-2 Stimulates T cells to proliferate & increases immunity/tumor necrosis.
IL-2,IL-4,IL-6 & Interferon -incites killer cells to attack specific target or antigen or cancer cells

B Cells and Antibodies
Antibodies are only produced by B lymphocytes.Antibodies bind antigen to produce immunoglobulins (igA,igD,E,G &M)which provide immediate short-term protection against disease for individuals who are at high risk of experiencing severe disease or of developing serious complications from the disease.

Boosters of Immune System:

Antioxidents, Vitamin C,E,A,B6,Betacrotin & Selenium. Fibre for digestion.HDL